Recombinant growth factors are proteins (polypeptides) that occur naturally in the body and are integral in the wound healing process. Research has determined that they stimulate cell growth and migration. Clinical efficacy has been demonstrated when they are used as an integral component of a comprehensive wound management program. Indicated for lower-extremity diabetic neuropathic ulcers. They are manufactured through recombinant DNA technology. Always read the package insert and use according to manufacturer's recommendations. Dress the wound according to protocol provided by the manufacturer.