Acute Wounds
Chronic Wounds
Deep Wounds
Dehisced Wounds
Diabetic Foot
Granulating/Epithelializing Wounds
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Pressure Ulcers
Superficial Wounds
Venous Ulcers

Preparation, Reconstitution and Surgical Use: Prior to implantation, carefully follow the EPIEFFECT™ allograft preparation steps below using aseptic technique: Wound Bed Preparation Ensure the wound is free from clinical sign of infection. Prepare wound bed as needed. Removing EPIEFFECT™ from Packaging The outer peel pouch is not sterile. The inner pouch that contains EPIEFFECT™ is sterile (unless the pouches are damaged or compromised). Carefully open the peelable corner of the outer pouch and extract the inner pouch using aseptic technique. Ensure the inner pouch does not come in contact with any portions of non-sterile surface of the outer pouch. Using aseptic technique, slowly peel a corner of the inner peel pouch and allow the authorized medical professional to grasp EPIEFFECT™ with fingers or non-toothed, sterile forceps. Use EPIEFFECT™ promptly after opening the inner, sterile pouch. Please take great care when removing EPIEFFECT™ from the internal pouch. EPIEFFECT™ is thin and extremely lightweight. EPIEFFECT™ Preparation In a dry state, use sterile dry scissors to cut EPIEFFECT™ to fit within the wound margins. It is acceptable to overlap the wound margins with EPIEFFECT™ by 1mm. If needed, EPIEFFECT™ can be fenestrated to accommodate wounds that produce copious amounts of exudate. EPIEFFECT™ can be applied wet or dry. EPIEFFECT™ can be hydrated while on the wound site with sterile saline solution. Simply apply several drops of sterile solution to EPIEFFECT™. During and following hydration, the embossment on EPIEFFECT™ will begin to fade. EPIEFFECT™ Orientation & Application EPIEFFECT™ should be placed on the wound site, using the orientation of the embossment lettering as a guide. Proper orientation of EPIEFFECT™ can be noted when the embossment nomenclature reads correctly from left to right. Absorbable, non-absorbable suture material and/or tissue adhesives can be used to fixate EPIEFFECT™ to the site of application or itself if desired. Support Therapies EPIEFFECT™ is compatible with offloading/compression/negative pressure therapies. EPIEFFECT™ can be used in conjunction with hyperbaric oxygen therapy. 

Primary Dressing EPIEFFECT™ should be covered with a non-adherent contact layer. EPIEFFECT™ should not be disturbed, if possible, for several days or before the next application, if needed. If an infection occurs at the graft site, treat infection per institution's protocol. Secondary Dressing EPIEFFECT™ requires a moist wound environment. Use appropriate moisture management dressings for the wound type and treatment ideology.