Acute Wounds
Burns
Cavity Wounds
Chronic Wounds
Deep Wounds
Dehisced Wounds
Diabetic Foot
Granulating/Epithelializing Wounds
Hypertrophic Scars/Keloids
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Palliative Wounds
Pressure Ulcers
Superficial Wounds
Surgical Wounds
Traumatic Wounds
Venous Ulcers

Membrane:
Salera® is packaged in a sterilized foil pouch that is designed to be passed directly into the sterile field. Use standard aseptic/sterile technique to open package.
1. Prepare wound area using standard methods to ensure wound is free of debris and necrotic tissue.
2. Peel open chevron seal of outer Tyvek pouch and pass inner foil pouch to sterile field.
3. Peel open chevron seal of inner pouch and remove tissue from inner pouch using sterile gloves/forceps.
4. In a dry state, use sterile dry scissors to trim Salera® to fit dimensions of application site. It is recommended no more than 0.5mm-2mm overlap over the wound margin.
5. Apply Salera® directly to patient site. If needed, membrane may be hydrated with sterile saline.
6. Anchor Salera® with tissue adhesives or by suturing the sheet, ensuring first that graft overlaps adjacent intact skin.
7. Use appropriate, non-adherent, primary dressing and secondary dressing to maintain a moist wound environment and the placement of the tissue.
NOTE: Ensure wound site is free of debris and necrotic tissue. Debride if necessary prior to graft placement. NOTE: Once foil pouch is opened, tissue should be used promptly. The opened innermost pouch alone is not intended for storage of tissue, as it may not provide an adequate moisture or sterile barrier.

Mini Membrane:
Salera®'s inner bottle and the outer foil pouch are sterilized. Use standard aseptic/sterile technique to open the package and make it ready for use.
Peel open the foil pouch and transfer the inner bottle as a single unit into the sterile field. Remove the white cap and aluminum collar from the bottle. Remove the rubber stopper. Note: The container should be held firmly on a hard surface while removing stopper to prevent spillage. Apply Salera® directly to the patient site. If needed, the tissue may be hydrated with sterile saline prior to or after application.
Note: Ensure the wound site is free of debris and necrotic tissue and debride if necessary prior to graft placement. Once the foil pouch is opened, tissue should be used promptly. Innermost bottle alone is not intended for storage of tissue, as it may not provide an adequate moisture or sterile barrier.
Note: The tissue must be implanted or discarded within 24 hours of opening the tissue container, provided the allograft tissue is maintained in an aseptic environment.

Dressings covering Salera® should be changed weekly or as needed.

Primary Dressing: Salera® should be covered with a non-adherent dressing.

Secondary Dressing: Salera® requires a moist wound environment. Use appropriate moisture management dressings for the wound type and treatment ideology.

To further encourage healing, patient should be appropriately offloaded following each visit as per institution's standard protocols.

Non-cytotoxic
Non-immunogenic
Non-irritating