Bioprinting: Also called three-dimensional (3D) bioprinting, this process combines 3D printing technologies with biomaterials to replicate parts that imitate natural tissues, bones, and blood vessels in the body. Chronic wounds: Wounds that fail to heal in an orderly and timely manner in 30 days. Complex wounds: A term clinicians may use to describe a wound that may have any number of complications, such as infection or chronicity. Common wounds that are classified as complex include fungating lesions, venous leg ulcers, diabetic foot ulcers, pressure injuries, open trauma, and wound fistulas.

Dermoconductive products: Cellular or tissue-based products that provide scaffolding within a healing wound that allows cells from surrounding tissue to migrate across the wound and create new tissue. Dermoinductive products: Cellular or tissue-based products derived from living cell cultures containing keratinocytes, fibroblasts, or both. These products recruit and activate tissue within the wound bed. Negative pressure wound therapy (NPWT): A wound treatment that uses a suction pump, tubing, and foam dressing to remove excess exudate and promote healing in complex wounds by applying subatmospheric pressure to the wound environment. Neodermis: A new layer of skin formed after a wound has healed. Imbibition, fibroblast migration, neovascularization, remodeling, and maturation are all distinct histologic phases of neodermis formation. Primary intention healing: Healing of a wound without tissue loss. With primary intention healing, the wound edges may be brought together or reapproximated for closure. Wound closure may occur with sutures, staples, adhesive tape, or glue. Secondary intention healing: Healing that occurs when the sides or edges of the wounds are not opposed. Therefore, the healing must occur from the bottom of the wound or wound bed and move upward. Myofibroblasts are crucial in secondary intention healing. Skin scaffolding: A process using skin or tissue scaffolds for grafting human skin. These scaffolds allow cells from the surrounding tissue to migrate across the wound and form new skin tissue. TIMERS: A framework for wound bed preparation. TIMERS is an acronym that represents the following components of wound care: tissue management, infection/inflammation, moisture balance, edge/epithelial advancements, regeneration/repair, and social factors.

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