Acute Wounds
Burns
Cavity Wounds
Chronic Wounds
Deep Wounds
Dehisced Wounds
Diabetic Foot
Granulating/Epithelializing Wounds
Moderate/Highly Exudating Wounds
Non/Minimally Exudating Wounds
Palliative Wounds
Pressure Ulcers
Sloughy Wounds
Superficial Wounds
Surgical Wounds
Venous Ulcers

These recommendations are designed to serve only as a general guideline. They are not intended to supersede institutional protocols or professional clinical judgment concerning patient care.
Prepare the wound bed by cleansing, irrigation and if necessary, debride to remove debris, necrotic tissue or infected tissue. Select a sheet of the Endoform™ Natural which is slightly larger than the wound and apply aseptically. Endoform™ Natural can be applied as a whole sheet or trimmed so that it contacts the wound margins. Multiple sheets can be used to cover the entire wound bed. For ease of handling, apply device by placing the dry material in the wound and rehydrating with exudate or sterile saline. When hydrated Endoform™ Natural transforms into a soft conforming sheet. Ensure that the device conforms to the underlying wound bed. To protect Endoform™ Natural from adhering to the secondary dressing, consider applying a non-adherent dressing over the device to help protect the tissue while facilitating an optimal moist wound healing environment. Secure the device using an appropriate secondary dressing. The secondary dressing should be changed according to standard of care, taking into account the level of exudate. Endoform™ Natural can be used in conjunction with compression therapy, off-loading, and negative pressure wound therapy.

Duration of treatment and reapplication is determined by the physician and depends upon the wound type and conditions. The biodegradable Endoform™ Natural is absorbed and incorporated into the wound over time. Reapply when the device has been incorporated into the wound. It is recommended to assess the wound within 72 hours. Endoform™ Natural may last up to 7 days in the wound, depending on the wound environment. Carefully cleanse the wound surface in accordance with established procedures. Do not attempt to remove the off-white to golden gel that forms from residual Endoform™ Natural in the wound as it contains extracellular matrix components that assist in wound healing. If areas of the device are dry upon inspection, rehydrate with sterile saline and leave in place. It is not necessary to remove any residual Endoform™ Natural during dressing changes. However, if the product has been overlapped onto the peri-wound area, the remaining loose product that has not incorporated into the wound may be gently removed around the edges if desired. Change the secondary dressings as needed according to standard of care, taking into account the level of exudate, and when Endoform™ Natural is re-applied.